166023-21-8

166023-21-8 structure

Name: DC-cholesterol hydrochloride
Chemical Name: Cholest-5-en-3-yl [2-(dimethylamino)ethyl]carbamate hydrochloride (1:1)
CAS Number: 166023-21-8
Molecular Formula: C₃₂H₅₇ClN₂O₂
Molecular Weight: 537.26000
Catalog: Research Areas Neurological Disease
Create Date: 2018-12-23 19:35:46
Modify Date: 2024-01-02 16:28:13
DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner[1][2].

Name	Cholest-5-en-3-yl [2-(dimethylamino)ethyl]carbamate hydrochloride (1:1)
Synonyms	2,3-dihydroxypropyl dihydrogen phosphate-cyclohexanamine(2:1) DC-cholesterol hydrochloride marinobufotoxin 3β-[N-(Dimethylaminoethane)carbamoyl]cholesterol O-[(N,N-Dimethylaminoethyl)-carbamoyl]cholesterol hydrochloride

Description	DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner[1][2].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Esmail A Elbassal, et al. Effects of Charged Cholesterol Derivatives on Aβ40 Amyloid Formation. J Phys Chem B. 2016 Jan 14;120(1):59-68. [2]. Richard Lantz, et al. Effects of disulfide bond and cholesterol derivatives on human calcitonin amyloid formation. Biopolymers. 2020 May;111(5):e23343.

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