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China
Product Name: Chondroitin 4-sulfate
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DC Chemicals Limited
China
Product Name: Chondroitin 4-sulfate
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Chodroitin Sulfate
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Henan Tianfu Chemical Co., Ltd.
China
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24967-93-9

24967-93-9 structure

24967-93-9 structure

Name: Chondroitin 4-sulfate
Chemical Name: chondroitin 4'-sulfate
CAS Number: 24967-93-9
Molecular Formula: C₁₃H₂₁NO₁₅S
Molecular Weight: 463.368
Catalog: API Circulatory system medication Regulating blood lipids
Create Date: 2018-02-24 08:00:00
Modify Date: 2024-01-02 15:23:04
Chondroitin 4-sulfate is a polyanion that can be found in human glioma tissues. Chondroitin 4-sulfate can promote the activation of pepsinogen[1].

Name	chondroitin 4'-sulfate
Synonyms	(2S,3S,4S,5R,6R)-6-{[(2R,3R,4R,5R,6R)-3-Acetamido-2,5-dihydroxy-6 -(sulfooxy)tetrahydro-2H-pyran-4-yl]oxy}-3,4,5-trihydroxytetrahyd ro-2H-pyran-2-carboxylic acid (non-preferred name) (2S,3S,4S,5R,6R)-6-{[(2R,3R,4R,5R,6R)-3-Acetamido-2,5-dihydroxy-6-(sulfooxy)tetrahydro-2H-pyran-4-yl]oxy}-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid 2-[(R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-hexadecahydrocyclopenta[a]phenanthren-17-yl)pentanoylamino]ethanesulfonic acid

Description	Chondroitin 4-sulfate is a polyanion that can be found in human glioma tissues. Chondroitin 4-sulfate can promote the activation of pepsinogen[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Horowitz MI, et, al. Promotion of activation of pepsinogen by polyanions including RNA and sulfated mucosubstances. Proc Soc Exp Biol Med. 1970 Mar;133(3):853-7. [2]. Pan H, et, al. Expression and function of chondroitin 4-sulfate and chondroitin 6-sulfate in human glioma. FASEB J. 2020 Feb;34(2):2853-2868.

Density	1.9±0.1 g/cm3
Molecular Formula	C₁₃H₂₁NO₁₅S
Molecular Weight	463.368
Exact Mass	463.063202
PSA	270.71000
LogP	-3.96
Index of Refraction	1.662

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GA8431500

CHEMICAL NAME :: Chondroitinsulfuric acids, type A

CAS REGISTRY NUMBER :: 24967-93-9

LAST UPDATED :: 199112

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >15 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHHTAT Zhonghua Yixue Zazhi. Chinese Medical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1915- Suspended 1967-72. Volume(issue)/page/year: 58,739,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1580 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHHTAT Zhonghua Yixue Zazhi. Chinese Medical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1915- Suspended 1967-72. Volume(issue)/page/year: 58,739,1978

WGK Germany	3
HS Code	2932999099

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%