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212790-31-3

212790-31-3 structure
212790-31-3 structure
  • Name: CP-481715
  • Chemical Name: N-[(2S,3S,5R)-5-carbamoyl-1-(3-fluorophenyl)-3,8-dihydroxy-8-methylnonan-2-yl]quinoxaline-2-carboxamide
  • CAS Number: 212790-31-3
  • Molecular Formula: C26H31FN4O4
  • Molecular Weight: 482.54700
  • Create Date: 2017-10-07 06:17:33
  • Modify Date: 2025-08-20 19:37:27
  • CP-481715 is a potent and selective CCR1 antagonist with Ki of 9.2 nM and IC50 of 74 nM, lacks intrinsic agonist activity and .
Name N-[(2S,3S,5R)-5-carbamoyl-1-(3-fluorophenyl)-3,8-dihydroxy-8-methylnonan-2-yl]quinoxaline-2-carboxamide
Synonyms cp-481,715
Molecular Formula C26H31FN4O4
Molecular Weight 482.54700
Exact Mass 482.23300
PSA 142.91000
LogP 4.23810
624736-64-7 structure

624736-64-7

~%

212790-31-3 structure

212790-31-3

Literature: Brown, Matthew F.; Avery, Mike; Brissette, William H.; Chang; Colizza, Kevin; Conklyn, Maryrose; DiRico, Amy P.; Gladue, Ronald P.; Kath, John C.; Krueger, Suzanne S.; Lira, Paul D.; Lillie, Brett M.; Lundquist, Greg D.; Mairs, Erin N.; McElroy, Eric B.; McGlynn, Molly A.; Paradis, Timothy J.; Poss, Christopher S.; Rossulek, Michelle I.; Shepard, Richard M.; Sims, Jeff; Strelevitz, Timothy J.; Truesdell, Susan; Tylaska, Laurie A.; Yoon, Kwansik; Zheng, Deye Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2175 - 2179
870-63-3 structure

870-63-3

~%

212790-31-3 structure

212790-31-3

Literature: Li, Bryan; Andresen, Brian; Brown, Matthew F.; Buzon, Richard A.; Chiu, Charles K.-F.; Couturier, Michel; Dias, Eric; Urban, Frank J.; Jasys, V. John; Kath, John C.; Kissel, William; Le, Tung; Li, Z. Jane; Negri, Joanna; Poss, Christopher S.; Tucker, John; Whritenour, David; Zandi, Kathleen Organic Process Research and Development, 2005 , vol. 9, # 4 p. 466 - 471
54745-92-5 structure

54745-92-5

~%

212790-31-3 structure

212790-31-3

Literature: Brown, Matthew F.; Avery, Mike; Brissette, William H.; Chang; Colizza, Kevin; Conklyn, Maryrose; DiRico, Amy P.; Gladue, Ronald P.; Kath, John C.; Krueger, Suzanne S.; Lira, Paul D.; Lillie, Brett M.; Lundquist, Greg D.; Mairs, Erin N.; McElroy, Eric B.; McGlynn, Molly A.; Paradis, Timothy J.; Poss, Christopher S.; Rossulek, Michelle I.; Shepard, Richard M.; Sims, Jeff; Strelevitz, Timothy J.; Truesdell, Susan; Tylaska, Laurie A.; Yoon, Kwansik; Zheng, Deye Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2175 - 2179
1026721-04-9 structure

1026721-04-9

~%

212790-31-3 structure

212790-31-3

Literature: Brown, Matthew F.; Avery, Mike; Brissette, William H.; Chang; Colizza, Kevin; Conklyn, Maryrose; DiRico, Amy P.; Gladue, Ronald P.; Kath, John C.; Krueger, Suzanne S.; Lira, Paul D.; Lillie, Brett M.; Lundquist, Greg D.; Mairs, Erin N.; McElroy, Eric B.; McGlynn, Molly A.; Paradis, Timothy J.; Poss, Christopher S.; Rossulek, Michelle I.; Shepard, Richard M.; Sims, Jeff; Strelevitz, Timothy J.; Truesdell, Susan; Tylaska, Laurie A.; Yoon, Kwansik; Zheng, Deye Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2175 - 2179
Precursor  3

DownStream  0

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