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64363-77-5

64363-77-5 structure
64363-77-5 structure
  • Name: Methyl 2,3,5-tri-O-benzyl-D-ribofuranoside
  • Chemical Name: (3R,4R,5R)-2-methoxy-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolane
  • CAS Number: 64363-77-5
  • Molecular Formula: C27H30O5
  • Molecular Weight: 434.52
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2017-04-04 02:22:28
  • Modify Date: 2024-01-11 15:46:31
  • Methyl 2,3,5-tri-O-benzyl-D-ribofuranoside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name (3R,4R,5R)-2-methoxy-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolane
Synonyms 2,3,5-tri-O-benzyl-1-O-methyl-D-ribose
Methyl 2,3,5-tri-O-benzyl-D-ribofuranoside
methyl 2,3,4-tri-O-benzylribofuranoside
methyl-2,3,5-tri-O-benzyl-D-riboside
D-Ribofuranoside, methyl 2,3,5-tris-O-(phenylmethyl)-
methyl tri-O-benzyl-D-ribofuranoside
Description Methyl 2,3,5-tri-O-benzyl-D-ribofuranoside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 1.2±0.1 g/cm3
Boiling Point 552.6±50.0 °C at 760 mmHg
Molecular Formula C27H30O5
Molecular Weight 434.52
Flash Point 217.4±30.0 °C
Exact Mass 434.209320
PSA 46.15000
LogP 6.48
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.587
Precursor  0

DownStream  2