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103654-50-8

103654-50-8 structure
103654-50-8 structure
  • Name: Puerarin apioside
  • Chemical Name: Mirificin
  • CAS Number: 103654-50-8
  • Molecular Formula: C26H28O13
  • Molecular Weight: 548.493
  • Catalog: Research Areas Endocrinology
  • Create Date: 2018-10-17 15:47:57
  • Modify Date: 2024-01-03 19:07:56
  • Mirificin (Puerarin apioside) is a isoflavone in Puerariae Lobatae Radix. Mirificin inhibits tyrosinase (TYR) with an IC50 of 12.66 μM[1].

Name Mirificin
Synonyms (1S)-1,5-Anhydro-6-O-[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-1-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl]-D-glucitol
mirificin
D-Glucitol, 1,5-anhydro-1-C-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-8-yl]-6-O-[(2R,3R,4R)-tetrahydro-3,4-dihydroxy-4-(hydroxymethyl)-2-furanyl]-, (1S)-
(1S)-1,5-anhydro-6-O-[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl]-1-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl]-D-glucitol
Puerarin apioside
Description Mirificin (Puerarin apioside) is a isoflavone in Puerariae Lobatae Radix. Mirificin inhibits tyrosinase (TYR) with an IC50 of 12.66 μM[1].
Related Catalog
Target

IC50: 12.66 μM (TYR)[1]

References

[1]. Liu H, et al. Enzyme-Site Blocking Combined with Optimization of Molecular Docking for Efficient Discovery of Potential Tyrosinase Specific Inhibitors from Puerariae lobatae Radix. Molecules. 2018 Oct 11;23(10).

Density 1.7±0.1 g/cm3
Boiling Point 848.0±65.0 °C at 760 mmHg
Molecular Formula C26H28O13
Molecular Weight 548.493
Flash Point 285.8±27.8 °C
Exact Mass 548.153015
PSA 219.74000
LogP 1.21
Vapour Pressure 0.0±3.3 mmHg at 25°C
Index of Refraction 1.749
Storage condition 2-8℃