115607-61-9
115607-61-9 structure
- Name: SKF96067
- Chemical Name: 1-[8-methoxy-4-(2-methylanilino)quinolin-3-yl]butan-1-one
- CAS Number: 115607-61-9
- Molecular Formula: C21H22N2O2
- Molecular Weight: 334.41200
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Proton Pump
- Create Date: 2017-03-23 22:27:22
- Modify Date: 2024-01-14 10:49:50
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SKF96067 is a reversible inhibitor of the gastric H+/K+-ATPase.
| Name | 1-[8-methoxy-4-(2-methylanilino)quinolin-3-yl]butan-1-one |
|---|---|
| Synonyms | SKF96067 |
| Description | SKF96067 is a reversible inhibitor of the gastric H+/K+-ATPase. |
|---|---|
| Related Catalog | |
| In Vitro | SKF96067 inhibits K+-stimulated ATPase activity competitively with respect to the activating action K+, with a Ki value of 0.39 ± 0.05 μM. SKF96067 also inhibits hydrogen ion transport. SKF96067 inhibits ATPase activity with an IC50 value of 60 ± 10 μM at pH 7.0, in the presence of 100 mM NaCl and 1 mM KCl[1]. |
| References |
| Density | 1.162g/cm3 |
|---|---|
| Boiling Point | 473.2ºC at 760mmHg |
| Molecular Formula | C21H22N2O2 |
| Molecular Weight | 334.41200 |
| Flash Point | 240ºC |
| Exact Mass | 334.16800 |
| PSA | 51.22000 |
| LogP | 5.35120 |
| Vapour Pressure | 4E-09mmHg at 25°C |
| Index of Refraction | 1.63 |
| Storage condition | 2-8℃ |