1041-90-3

1041-90-3 structure
1041-90-3 structure
  • Name: nalorphine hydrobromide
  • Chemical Name: (4R,4aR,7S,7aR,12bS)-9-methoxy-3-prop-2-enyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol,hydrobromide
  • CAS Number: 1041-90-3
  • Molecular Formula: C19H22BrNO3
  • Molecular Weight: 392.28700
  • Catalog: API Special medicine Antidote
  • Create Date: 2018-02-20 08:00:00
  • Modify Date: 2024-01-11 12:29:09

Name (4R,4aR,7S,7aR,12bS)-9-methoxy-3-prop-2-enyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol,hydrobromide
Synonyms N-Allylnormorphine hydrobromide
Nalorphine hydrobromide
C19H21NO3.HBr
Nalorphine bromide
EINECS 213-868-2
Boiling Point 493.6ºC at 760mmHg
Melting Point 208ºC
Molecular Formula C19H22BrNO3
Molecular Weight 392.28700
Flash Point 252.3ºC
Exact Mass 391.07800
PSA 52.93000
LogP 2.65030
Vapour Pressure 1.46E-10mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QC7705000
CHEMICAL NAME :
Morphinan-3,6-alpha-diol, 17-allyl-7,8-didehydro-4,5-alpha-epoxy-, hydrobromide
CAS REGISTRY NUMBER :
1041-90-3
LAST UPDATED :
199512
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H21-N-O3.Br-H
MOLECULAR WEIGHT :
392.33

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
260 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 51,199,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
921 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 21,668,1969