5868-06-4
5868-06-4 structure
- Name: Fentonium
- Chemical Name: [8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate,bromide
- CAS Number: 5868-06-4
- Molecular Formula: C31H34BrNO4
- Molecular Weight: 564.51000
- Catalog: Research Areas Neurological Disease
- Create Date: 2018-05-24 08:00:00
- Modify Date: 2024-01-21 15:14:43
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Fentonium bromide is an anti-ulcerogenic, anticholinergic and antispasmodic agent. Fentonium bromide can be used in the research of neurological conditions[1][2][3].
| Name | [8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate,bromide |
|---|---|
| Synonyms |
Fentonio bromuro [DCIT]
Ulcesium Z 326 Fentonii bromidum [INN-Latin] Bromure de fentonium [INN-French] FA 402 Ketoscilium Fentonium bromide Phentonium bromide |
| Description | Fentonium bromide is an anti-ulcerogenic, anticholinergic and antispasmodic agent. Fentonium bromide can be used in the research of neurological conditions[1][2][3]. |
|---|---|
| Related Catalog | |
| In Vivo | Fentonium bromide (1 mg/kg, i.v.) is an effective antagonist of gastric secretion in rats[1]. Fentonium bromide (phentonium, 1 mg/kg, i.p.) prevents stress ulcers in rats[1]. Animal Model: Bethanechol-, pentagastrin-, and caerulein-induced gastric secretion in rats[1] Dosage: 1 mg/kg Administration: Intravenous injection (i.v.) Result: Inhibited gastric acid secretion. Animal Model: Rats[2] Dosage: 1 mg/kg Administration: Intraperitoneal injection (i.p.) Result: Decreased both the number of pre-ulceral lesions and the number of gastroduodenal ulcers in comparison with untreated controls. |
| Molecular Formula | C31H34BrNO4 |
|---|---|
| Molecular Weight | 564.51000 |
| Exact Mass | 563.16700 |
| PSA | 63.60000 |
| LogP | 1.95840 |