CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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SY9299000
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CHEMICAL NAME :
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Phosphine oxide, P,P-bis(1-aziridinyl)-P-(1-adamantyl)-
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CAS REGISTRY NUMBER :
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64693-33-0
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LAST UPDATED :
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199612
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DATA ITEMS CITED :
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4
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MOLECULAR FORMULA :
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C14-H23-N2-O-P
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MOLECULAR WEIGHT :
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266.36
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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75 mg/kg
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SEX/DURATION :
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male 5 day(s) pre-mating
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TOXIC EFFECTS :
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Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
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REFERENCE :
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JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 21,143,1978
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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169 mg/kg
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SEX/DURATION :
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male 5 day(s) pre-mating
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TOXIC EFFECTS :
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Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
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REFERENCE :
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JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 21,143,1978
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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DOSE :
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75 mg/kg
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SEX/DURATION :
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male 5 day(s) pre-mating
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TOXIC EFFECTS :
-
Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
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REFERENCE :
-
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 21,143,1978
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TYPE OF TEST :
-
TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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DOSE :
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112 mg/kg
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SEX/DURATION :
-
male 5 day(s) pre-mating
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TOXIC EFFECTS :
-
Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
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REFERENCE :
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JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 21,143,1978
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