105355-26-8
- Name: Pioglitazone 2-Imine
- Chemical Name: Pioglitazone 2-Imine
- CAS Number: 105355-26-8
- Molecular Formula: C19H21N3O2S
- Molecular Weight: 355.454
- Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridine compound Ethylpyridine
- Create Date: 2018-06-27 18:22:44
- Modify Date: 2025-08-20 18:00:58
| Name | Pioglitazone 2-Imine |
|---|---|
| Synonyms |
2-Amino-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazol-4(5H)-one
5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4-thiazolidinone 4(5H)-Thiazolone, 2-amino-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]- 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]-2-imino-4-thiazolidinone 2-Amino-5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazol-4(5H)-one 5-{4-[5-(ethylpyridin-2-yl)ethoxy]benzyl}-2-iminothiazolidin-4-one MFCD07368032 5-{4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzyl}-2-imino-1,3-thiazolidin-4-one 2-Amino-5-{4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzyl}-1,3-thiazol-4(5H)-one Pioglitazone Impurity 14 |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 557.4±60.0 °C at 760 mmHg |
| Melting Point | 187-188ºC |
| Molecular Formula | C19H21N3O2S |
| Molecular Weight | 355.454 |
| Flash Point | 290.9±32.9 °C |
| Exact Mass | 355.135437 |
| PSA | 102.87000 |
| LogP | 2.57 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.646 |
| Storage condition | Refrigerator |
| HS Code | 2934999090 |
|---|
|
~58%
105355-26-8 |
| Literature: MOREPEN LABORATORIES LIMITED Patent: WO2006/35459 A1, 2006 ; Location in patent: Page/Page column 24; 25 ; |
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| Literature: WO2009/133576 A1, ; Page/Page column 7 ; |
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| Literature: WO2008/75380 A2, ; Page/Page column 15 ; |
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| Literature: WO2008/75380 A2, ; Page/Page column 16 ; |
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105355-26-8 |
| Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 1 p. 37 - 42 |
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| Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 1 p. 37 - 42 |
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~%
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| Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 1 p. 37 - 42 |
|
~51%
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| Literature: Sohda; Momose; Meguro; Kawamatsu; Sugiyama; Ikeda Arzneimittel-Forschung/Drug Research, 1990 , vol. 40, # 1 p. 37 - 42 |
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~%
105355-26-8 |
| Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 1 p. 37 - 42 |
| Precursor 9 | |
|---|---|
| DownStream 2 | |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |