105355-26-8
105355-26-8 structure
- Name: Pioglitazone 2-Imine
- Chemical Name: Pioglitazone 2-Imine
- CAS Number: 105355-26-8
- Molecular Formula: C19H21N3O2S
- Molecular Weight: 355.454
- Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridine compound Ethylpyridine
- Create Date: 2018-06-27 18:22:44
- Modify Date: 2026-07-01 22:49:00
| Name | Pioglitazone 2-Imine |
|---|---|
| Synonyms |
2-Amino-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-4(5H)-thiazolone
5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]Methyl]-2-iMino-4-thiazolidinone 5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4-thiazoli 5-{4-[2-(5-ETHYL-2-PYRIDYL)ETHOXY]BENZYL}-2-IMINO-4-THIAZOLIDINONE(FOR PIOGLITAZONE) 5-{4-[2-(5-Ethyl-2-pyridinyl) ethoxy] benzyl}-2-imino-4-thiazolidinedione ( 5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4-thiazolidinone 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]-2-imino-4-thiazolidinone 4(5H)-Thiazolone,2-amino-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl] 2-AMINO-5-(4-[2-(5-ETHYL-PYRIDIN-2-YL)-ETHOXY]-BENZYL)-THIAZOL-4-ONE 5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4-thiazolidinone ISO 9001：2015 REACH 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)-2-iMinothiazolidin-4 5-{4-[2-(5-ETHYL-2-PYRIDY)ETHOXY]BENZYL}-2-IMINO-4-THIAZOLIDINONE Imino-Pioglitazone 2-Amino-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazol-4(5H)-one (5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4-thiazolidone) 5-{4-[2-(5-Ethyl-2-Pyridyl)Ethoxy]Benzyl}-2-Imino-4-Thiazolidinone [PBIT] 2-AMINO-5-[4-[2-(5-ETHYL-2-PYRIDYL)ETHOXY]BENZYL]-4(5H)-THIAZOLONE MFCD07368032 2-Amino-5-{4-[2-(5-ethyl-pyridin-2-yl)-ethoxy] TIANFU 5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4-thiazolidinone 2-Amino-5-[4-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl]thiazol-4(5H)-one Pioglitazone impurities1592 2-Amino-5-[4-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl]thiazol-4(5H)-one > 2-Amino-5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazol-4(5H)-one 5-{4-[2-(5-ETHYL-2-PYRIDYL)ETHOXY]BENZYL}-2-AMINO-4-THIAZOLIDINONE 2-Amino-5-{4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzyl}-1,3-thiazol-4(5H)-one 5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}Methyl)-2-iMino-1,3-thiazolidin-4-one Pioglitazone 2-imine 5-{4-[5-(ethylpyridin-2-yl)ethoxy]benzyl}-2-iminothiazolidin-4-one Pioglitazone Impurity 14 5-{[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methy}-2-imino-4-thiazolidinone Pioglitazone IMino IMpurity 5-{4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzyl}-2-imino-1,3-thiazolidin-4-one 2-Amino-5-[[4-[2-(5-ethyl-2-pyridyl)ethoxy]phenyl]methyl]thiazol-4-one |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 557.4±60.0 °C at 760 mmHg |
| Melting Point | 187-188ºC |
| Molecular Formula | C19H21N3O2S |
| Molecular Weight | 355.454 |
| Flash Point | 290.9±32.9 °C |
| Exact Mass | 355.135437 |
| PSA | 102.87000 |
| LogP | 2.57 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.646 |
| Storage condition | Refrigerator |
| HS Code | 2934999090 |
|---|
|
~58%
105355-26-8 |
| Literature: MOREPEN LABORATORIES LIMITED Patent: WO2006/35459 A1, 2006 ; Location in patent: Page/Page column 24; 25 ; |
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| Literature: WO2009/133576 A1, ; Page/Page column 7 ; |
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| Literature: WO2008/75380 A2, ; Page/Page column 15 ; |
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105355-26-8 |
| Literature: WO2008/75380 A2, ; Page/Page column 16 ; |
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~%
105355-26-8 |
| Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 1 p. 37 - 42 |
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~%
105355-26-8 |
| Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 1 p. 37 - 42 |
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105355-26-8 |
| Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 1 p. 37 - 42 |
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~51%
105355-26-8 |
| Literature: Sohda; Momose; Meguro; Kawamatsu; Sugiyama; Ikeda Arzneimittel-Forschung/Drug Research, 1990 , vol. 40, # 1 p. 37 - 42 |
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~%
105355-26-8 |
| Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 1 p. 37 - 42 |
| Precursor 9 | |
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| DownStream 2 | |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |