Top Suppliers:I want be here


  • DC Chemicals Limited
  • China
  • Product Name: ICI 204636
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

111974-69-7

111974-69-7 structure
111974-69-7 structure
  • Name: Quetiapine
  • Chemical Name: quetiapine
  • CAS Number: 111974-69-7
  • Molecular Formula: C21H25N3O2S
  • Molecular Weight: 383.507
  • Catalog: API Nervous system medication Antipsychotic
  • Create Date: 2018-02-04 08:00:00
  • Modify Date: 2024-01-03 00:03:36
  • Quetiapine(Ketipinor) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.IC50 value: Target: 5-HT ReceptorQuetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor.

Name quetiapine
Synonyms [14C]-Quetiapine
quetiapina
2-{2-4-(dibenzob,f1,4thiazepin-11-yl)piperazin-1-ylethoxy}ethanol
11-(4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl)-dibenzo[b,f][1,4]thiazepine
MFCD08064204
Seroquel
2-(2-(4-dibenzo[b,f][1,4]thiazepine-11-yl-1-piperazinyl)ethoxy)ethanol
UNII-BGL0JSY5SI
11-[4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl]dibenzo[b,f][1,4]thiazepine
2-[2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethoxy]ethanol
Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-
2-{[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethyl]oxy}ethanol
ethanol, 2-2-(4-dibenzob,f1,4thiazepin-11-yl-1-piperazinyl)ethoxy-
Co-Quetiapine
2-{2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethoxy}ethanol
quetiapinum
2-{2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy}ethanol
Quetiapine [INN:BAN]
2-(2-(4-Dibenzo(b,f)(1,4)thiazepine-11-yl-1-piperazinyl)ethoxy)ethanol
Description Quetiapine(Ketipinor) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.IC50 value: Target: 5-HT ReceptorQuetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor.
Related Catalog
References

[1]. Sheehan DV, et al. Long-term functioning and sleep quality in patients with major depressive disorder treated with extended-release quetiapine fumarate. Int Clin Psychopharmacol. 2012 Sep;27(5):239-48.

[2]. Endicott J, et al. Effects of once-daily extended release quetiapine fumarate on patient-reported outcomes in patients with generalized anxiety disorder. Neuropsychiatr Dis Treat. 2012;8:301-311.

[3]. Lee JG, et al. Safety of quetiapine fumarate extended release in the treatment of Korean patients with acute schizophrenia. Hum Psychopharmacol. 2012 Jul;27(4):403-10. doi: 10.1002/hup.2241.

[4]. Thase ME, et al. Extended release quetiapine fumarate in major depressive disorder: analysis in patients with anxious depression. Depress Anxiety. 2012 Jul;29(7):574-86. doi: 10.1002/da.21970.

[5]. Katila H, et al. Randomized, Double-Blind Study of the Efficacy and Tolerability of Extended Release Quetiapine Fumarate (Quetiapine XR) Monotherapy in Elderly Patients With Major Depressive Disorder.Am J Geriatr Psychiatry. 2012 Jun 7.

Density 1.3±0.1 g/cm3
Boiling Point 556.5±60.0 °C at 760 mmHg
Melting Point 172 - 174ºC
Molecular Formula C21H25N3O2S
Molecular Weight 383.507
Flash Point 290.4±32.9 °C
Exact Mass 383.166748
PSA 73.60000
LogP 1.57
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.653
Storage condition -20℃
HS Code 2934999090
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%