819048-44-7

819048-44-7 structure

Name: Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide trifluoroacetate salt
Chemical Name: ac-d-arg-cys-glu-his-d-phe-arg-trp-cys-nh2
CAS Number: 819048-44-7
Molecular Formula: C₅₁H₇₂N₁₈O₁₁S₂
Molecular Weight: 1177.36000
Catalog: Research Areas Cardiovascular Disease
Create Date: 2017-08-07 20:49:34
Modify Date: 2024-02-18 17:44:18
Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH 2 is a cyclic octapeptide with MC4R agonism. Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH 2 significantly increases heart rate and blood pressure[1].

Name	ac-d-arg-cys-glu-his-d-phe-arg-trp-cys-nh2

Description	Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH 2 is a cyclic octapeptide with MC4R agonism. Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH 2 significantly increases heart rate and blood pressure[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Melanocortin Receptor
References	[1]. Doering SR, et al. Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput "Unbiased" Screening Campaign. J Med Chem. 2021 May 13;64(9):5577-5592. doi: 10.1021/acs.jmedchem.0c02041. Epub 2021 Apr 22. Erratum in: J Med Chem. 2023 May 25;66(10):7063-7065.