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18910-65-1

18910-65-1 structure
18910-65-1 structure
  • Name: Salmefamol
  • Chemical Name: 4-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]-2-(hydroxymethyl)phenol
  • CAS Number: 18910-65-1
  • Molecular Formula: C19H25NO4
  • Molecular Weight: 331.40600
  • Catalog: API Respiratory medication Asthma
  • Create Date: 2018-08-07 10:40:06
  • Modify Date: 2024-01-13 17:18:08
  • Salmeterol is a long-acting beta2-adrenergic receptor agonist drug used in the maintenance and prevention of asthma symptoms and maintenance of chronic obstructive pulmonary disease (COPD) symptoms. Symptoms include shortness of breath, wheezing, coughing and chest tightness. Salmeterol is also used to prevent breathing difficulties during exercise (exercise induced bronchospasm). It is marketed as Serevent in the US.

Name 4-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]-2-(hydroxymethyl)phenol
Synonyms Salmefamolum [INN-Latin]
AHR 3929
AH-3923
a-((p-methoxy-a-methylphenethylamino)methyl)-4-hydroxy-m-xylene-a,a'-diol
Salmefamol
EINECS 242-662-5
Density 1.2g/cm3
Boiling Point 553.4ºC at 760mmHg
Molecular Formula C19H25NO4
Molecular Weight 331.40600
Flash Point 288.5ºC
Exact Mass 331.17800
PSA 81.95000
LogP 2.53820
Vapour Pressure 4.43E-13mmHg at 25°C
Index of Refraction 1.598

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CZ6438000
CHEMICAL NAME :
1,3-Benzenedimethanol, 4-hydroxy-alpha(sup 1)-(((2-(4-methoxyphenyl)-1-methylethyl)amino) methyl)-
CAS REGISTRY NUMBER :
18910-65-1
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H25-N-O4
MOLECULAR WEIGHT :
331.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PGMJAO Postgraduate Medical Journal. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1925- Volume(issue)/page/year: 51,627,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PGMJAO Postgraduate Medical Journal. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1925- Volume(issue)/page/year: 51,627,1975