14919-49-4

14919-49-4 structure
14919-49-4 structure
  • Name: 3,4'-Dihydroxyflavone
  • Chemical Name: 3-hydroxy-2-(4-hydroxyphenyl)chromen-4-one
  • CAS Number: 14919-49-4
  • Molecular Formula: C15H10O4
  • Molecular Weight: 254.24
  • Catalog: Signaling Pathways Anti-infection Influenza Virus
  • Create Date: 2018-04-11 08:00:00
  • Modify Date: 2024-01-03 18:03:49
  • 3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus[1].

Name 3-hydroxy-2-(4-hydroxyphenyl)chromen-4-one
Synonyms 3-Hydroxy-2-(4-hydroxyphenyl)chromone
4'-Hydroxyflavonol
3-hydroxy-2-(4-hydroxy-phenyl)-chromen-4-one
3,4'-dihydroxyfavone
3-Hydroxy-2-(4-hydroxy-phenyl)-chromen-4-on
3,4'-dihydroxyfalvone
3,4'-Dihydroxyflavone
Description 3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus[1].
Related Catalog
In Vivo 3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1]. Animal Model: 3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1]. Dosage: 1 mg/kg per 30 μL. Administration: Oral administration daily for 5 days. Result: Significantly decreased virus titers and pathological changes in the lung and reduced body weight loss and death.
References

[1]. Hossain MK, et al. Antiviral activity of 3,4'-dihydroxyflavone on influenza a virus. J Microbiol. 2014 Jun;52(6):521-6.

Density 1.472g/cm3
Boiling Point 452.5ºC at 760mmHg
Melting Point 275-276ºC
Molecular Formula C15H10O4
Molecular Weight 254.24
Flash Point 175.7ºC
Exact Mass 254.05800
PSA 70.67000
LogP 2.87120
Vapour Pressure 5.61E-09mmHg at 25°C
Index of Refraction 1.712
HS Code 2914501900
HS Code 2914501900
Summary 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%