Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Tomoxiprole
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Purity: 98.0%
Stocking Period: Inquiry
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76145-76-1

76145-76-1 structure

Name: Tomoxiprole
Chemical Name: 2-(4-methoxyphenyl)-3-propan-2-ylbenzo[e]benzimidazole
CAS Number: 76145-76-1
Molecular Formula: C₂₁H₂₀N₂O
Molecular Weight: 316.39600
Create Date: 2018-06-26 11:12:06
Modify Date: 2024-01-09 11:23:03

Name	2-(4-methoxyphenyl)-3-propan-2-ylbenzo[e]benzimidazole
Synonyms	Tomoxiprolum S085 3-(1-methylethyl)-2-(4-methoxyphenyl)-3H-naphth<1,2-d>imidazole UNII-EZ948T2878 Tomoxiprole MDL-035

Density	1.178g/cm3
Boiling Point	529.1ºC at 760 mmHg
Molecular Formula	C₂₁H₂₀N₂O
Molecular Weight	316.39600
Flash Point	186.5ºC
Exact Mass	316.15800
PSA	27.05000
LogP	5.44600
Index of Refraction	1.666

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QK9343000

CHEMICAL NAME :: 3H-Naphth(1,2-d)imidazole, 2-(4-methoxyphenyl)-3-(1-methylethyl)-

CAS REGISTRY NUMBER :: 76145-76-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C21-H20-N2-O

MOLECULAR WEIGHT :: 316.43

WISWESSER LINE NOTATION :: T B566 CN ENJ DR DO1& EY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJDPD2 European Journal of Drug Metabolism and Pharmacokinetics. (Medecine et Hygiene, POB 229, CH-1211 Geneva 4, Switzerland) V.1- 1976- Volume(issue)/page/year: 10,161,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,133,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,133,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,133,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,133,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,133,1985

HS Code	2933990090

76145-77-2

76145-76-1

Literature: Toja; Selva; Schiatti Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 610 - 616

131-91-9

76145-76-1

Literature: Toja; Selva; Schiatti Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 610 - 616

35624-23-8

76145-76-1

Literature: Toja; Selva; Schiatti Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 610 - 616

123-11-5

76145-76-1

Literature: Toja; Selva; Schiatti Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 610 - 616

Precursor 4
76145-77-2 131-91-9 35624-23-8 123-11-5
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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