14341-79-8

14341-79-8 structure
14341-79-8 structure
  • Name: DL-Glutamic acid-d5
  • Chemical Name: 2-amino-2,3,3,4,4-pentadeuteriopentanedioic acid
  • CAS Number: 14341-79-8
  • Molecular Formula: C5H4D5NO4
  • Molecular Weight: 152.160
  • Catalog: Research Areas Others
  • Create Date: 2018-08-20 18:09:47
  • Modify Date: 2024-04-02 12:02:24
  • DL-Glutamic acid-d5 is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].

Name 2-amino-2,3,3,4,4-pentadeuteriopentanedioic acid
Synonyms DL-Glutamic acid-2,3,3,4,4-d5
glutamic acid-d5
Glutamic-2,3,3,4,4-d acid
glutamic acid-2,3,3,4,4-d5
(2,3,3,4,4-H)Glutamic acid
2,3,3,4,4-pentadeuterio-glutamic acid
Description DL-Glutamic acid-d5 is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Density 1.4±0.1 g/cm3
Boiling Point 333.8±32.0 °C at 760 mmHg
Melting Point 185ºC (dec)(lit.)
Molecular Formula C5H4D5NO4
Molecular Weight 152.160
Flash Point 155.7±25.1 °C
Exact Mass 152.084549
PSA 100.62000
LogP -1.43
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.522
Storage condition 2-8°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport