146255-66-5

146255-66-5 structure
146255-66-5 structure
  • Name: (RS)-3,5-DHPG
  • Chemical Name: (S)-3,5-dihydroxyphenylglycine
  • CAS Number: 146255-66-5
  • Molecular Formula: C8H9NO4
  • Molecular Weight: 183.16100
  • Catalog: Biochemical Amino acids and their derivatives Glycine derivatives
  • Create Date: 2018-04-10 08:00:00
  • Modify Date: 2024-01-09 10:14:50
  • DHPG ((RS)-3,5-DHPG) is an amino acid, which acts as a selective and potent agonist of group I mGluR (mGluR 1 and mGluR 5), shows no effect on Group II or Group III mGluRs[1]. DHPG ((RS)-3,5-DHPG) is also an effective antagonist of mGluRs linked to phospholipase D[2].

Name (S)-3,5-dihydroxyphenylglycine
Synonyms (RS)-3,5-DHPG
tert-Butylisopentanal
HEXANAL,3,5,5-TRIMETHYL
Isononylaldehyde
3,5,5-Trimethylcapronaldehyde
3,5,5,-trimethylhexanal
Hexanal,3,5,5-trimethl
Description DHPG ((RS)-3,5-DHPG) is an amino acid, which acts as a selective and potent agonist of group I mGluR (mGluR 1 and mGluR 5), shows no effect on Group II or Group III mGluRs[1]. DHPG ((RS)-3,5-DHPG) is also an effective antagonist of mGluRs linked to phospholipase D[2].
Related Catalog
Target

mGluR 1

mGluR 5

References

[1]. Winder DG, et al. Metabotropic glutamate receptor (mGluR)-mediated potentiation of cyclic AMP responses does not require phosphoinositide hydrolysis: mediation by a group II-like mGluR. J Neurochem. 1995 Feb;64(2):592-9.

[2]. Pellegrini-Giampietro DE, et al. Pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase D in the rat hippocampus. Br J Pharmacol. 1996 Jun;118(4):1035-43.

Density 1.55g/cm3
Boiling Point 448.8ºC at 760mmHg
Molecular Formula C8H9NO4
Molecular Weight 183.16100
Flash Point 225.2ºC
Exact Mass 183.05300
PSA 103.78000
LogP 0.88250