83602-39-5
83602-39-5 structure
- Name: Cyclosporin H
- Chemical Name: Cyclosporin H
- CAS Number: 83602-39-5
- Molecular Formula: C62H111N11O12
- Molecular Weight: 1216.638
- Catalog: Signaling Pathways Others Others
- Create Date: 2018-04-24 08:00:00
- Modify Date: 2024-01-16 06:27:37
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Cyclosporin H, a viral transduction enhancer, increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). Cyclosporin H displays an additive effect when combined with Rapamycin or prostaglandin E2. Cyclosporin H lacks immunosuppressant activity of cyclosporin A.
| Name | Cyclosporin H |
|---|---|
| Synonyms |
(3S,6S,9S,12R,15S,18S,21R,24S,30S)-30-Ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methyl-4-hexen-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,22,25,28-decamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
CyclosporinH 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methyl-4-hexen-1-yl]-1,4,7,10,12,15,19,22,25,28-decamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S,6S,9S,12R,15S,18S,21R,24S,30S)- cyclosiversioside H Cyclosporin Impurity 8 |
| Description | Cyclosporin H, a viral transduction enhancer, increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). Cyclosporin H displays an additive effect when combined with Rapamycin or prostaglandin E2. Cyclosporin H lacks immunosuppressant activity of cyclosporin A. |
|---|---|
| Related Catalog |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 1282.0±65.0 °C at 760 mmHg |
| Melting Point | 162-165ºC |
| Molecular Formula | C62H111N11O12 |
| Molecular Weight | 1216.638 |
| Flash Point | 729.1±34.3 °C |
| Exact Mass | 1215.857056 |
| PSA | 270.01000 |
| LogP | 4.28 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.469 |