86099-06-1

86099-06-1 structure

Name: BM-PEG3
Chemical Name: 1,11-Bis(maleimido)tetraethyleneglycol
CAS Number: 86099-06-1
Molecular Formula: C₁₆H₂₀N₂O₇
Molecular Weight: 352.33900
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-10-06 09:52:25
Modify Date: 2024-01-22 12:00:07
BM-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1,11-Bis(maleimido)tetraethyleneglycol
Synonyms	1,11-Bis-Maleimidodriethyleneglycol

Description	BM-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.