87226-41-3

87226-41-3 structure

87226-41-3 structure

Name: (R)-(-)-Etodolac
Chemical Name: (R)-(-)-Etodolac
CAS Number: 87226-41-3
Molecular Formula: C₁₇H₂₁NO₃
Molecular Weight: 287.35400
Create Date: 2017-07-03 00:10:51
Modify Date: 2024-02-05 09:42:34

Name	(R)-(-)-Etodolac
Synonyms	(S)-ethyl-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido-[1,2,3-de]-1,4-benzoxazine-6-carboxylate (-)-ethyl-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido [1,2,3-de]-1,4-benzoxazine-6-carboxylate (R)-etodolac (S)-Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate (R)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid R-(-)-etodolic acid (S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester ethyl (S)-(-)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate [14C]-(R)-Etodolac (-)-etodolac

Density	1.165g/cm3
Boiling Point	452.6ºC at 760 mmHg
Molecular Formula	C₁₇H₂₁NO₃
Molecular Weight	287.35400
Flash Point	227.5ºC
Exact Mass	287.15200
PSA	62.32000
LogP	3.38300
Index of Refraction	1.581

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UQ0360010

CHEMICAL NAME :: Pyrano(3,4-b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1,8-diethyl-, (R)-

CAS REGISTRY NUMBER :: 87226-41-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C17-H21-N-O3

MOLECULAR WEIGHT :: 287.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 327 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 40,737,1990

Precursor 0
DownStream 2
41340-25-4 200880-27-9