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222035-13-4

222035-13-4 structure
222035-13-4 structure
  • Name: SC 221409
  • Chemical Name: 4-[(2Z)-2-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino ]benzenesulfonamide
  • CAS Number: 222035-13-4
  • Molecular Formula: C14H11BrN4O3S
  • Molecular Weight: 395.231
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
  • Create Date: 2016-11-19 03:22:23
  • Modify Date: 2024-01-12 19:10:15
  • CDK2-IN-3 (compound 3) is a potent and selective CDK2 inhibitor with an 50 of 60 nM[1].

Name 4-[(2Z)-2-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino ]benzenesulfonamide
Synonyms 4-[(2Z)-2-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinyl]benzenesulfonamide
4-[(2Z)-2-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]benzenesulfonamide
Benzenesulfonamide, 4-[(2Z)-2-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]-
Description CDK2-IN-3 (compound 3) is a potent and selective CDK2 inhibitor with an 50 of 60 nM[1].
Related Catalog
Target

CDK2:60 nM (IC50)

References

[1]. S T Davis, et al. Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors. Science. 2001 Jan 5;291(5501):134-7.  

Density 1.9±0.1 g/cm3
Molecular Formula C14H11BrN4O3S
Molecular Weight 395.231
Exact Mass 393.973511
PSA 122.03000
LogP 2.53
Index of Refraction 1.769