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1147350-75-1

1147350-75-1 structure
1147350-75-1 structure
  • Name: Clopidogrel thiolactone
  • Chemical Name: methyl (2S)-2-(2-chlorophenyl)-2-(2-oxo-4,6,7,7a-tetrahydrothieno[3,2-c]pyridin-5-yl)acetate
  • CAS Number: 1147350-75-1
  • Molecular Formula: C16H16ClNO3S
  • Molecular Weight: 337.821
  • Catalog: Signaling Pathways GPCR/G Protein P2Y Receptor
  • Create Date: 2016-08-10 05:34:28
  • Modify Date: 2024-01-03 06:36:56
  • Clopidogrel thiolactone is a P2Y12 receptor inhibitor, is a potent antiplatelet agent.Target: P2Y12Clopidogrel thiolactone is the metabolic intermediate resulting from the first oxidative activation of clopidogrel.

Name methyl (2S)-2-(2-chlorophenyl)-2-(2-oxo-4,6,7,7a-tetrahydrothieno[3,2-c]pyridin-5-yl)acetate
Synonyms (S)-methyl 2-(2-chlorophenyl)-2-(2-oxo-7,7a-dihydrothieno-[3,2-c]pyridin-5(2H,4H,6H)-yl)acetate
(2S)-Methyl 2-(2-chlorophenyl)-2-(2-oxo-7,7a-dihydrothieno[3,2-c]pyridin-5(2H,4H,6H)-yl)acetate
(2'S)-2-oxo-clopidogrel
[8S]-2-oxo-clopidogrel
clopidogrel thiolactone
Methyl (2S)-(2-chlorophenyl)(2-oxo-2,6,7,7a-tetrahydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
(2S)-methyl 2-(2-oxo-7,7a-dihydrothieno[3,2-c]pyridin-5(2H,4H,6H)-yl)-2-(2-chlorophenyl)acetate
Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-2,6,7,7a-tetrahydro-2-oxo-, methyl ester, (αS)-
2-Oxoclopidogrel
methyl (2'S)-2-(2-chlorophenyl)-2-(2,4,5,6,7,7a-hexahydrothieno[3,2-c]-5-pyridin-2-one)acetate
Description Clopidogrel thiolactone is a P2Y12 receptor inhibitor, is a potent antiplatelet agent.Target: P2Y12Clopidogrel thiolactone is the metabolic intermediate resulting from the first oxidative activation of clopidogrel.
Related Catalog
References

[1]. Shan J, et al. Overcoming Clopidogrel Resistance: Discovery of Vicagrel as a Highly Potent and Orally Bioavailable Antiplatelet Agent

Density 1.4±0.1 g/cm3
Boiling Point 488.1±45.0 °C at 760 mmHg
Molecular Formula C16H16ClNO3S
Molecular Weight 337.821
Flash Point 249.0±28.7 °C
Exact Mass 337.053955
PSA 71.91000
LogP 2.96
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.640
Storage condition 2-8℃
HS Code 2934999090
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%