CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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XS3591000
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CHEMICAL NAME :
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p-Toluamide, 2-(allyloxy)-N-(2-(diethylamino)ethyl)-alpha,alpha,al pha-trifluoro-
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CAS REGISTRY NUMBER :
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5107-49-3
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LAST UPDATED :
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199707
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DATA ITEMS CITED :
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4
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MOLECULAR FORMULA :
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C17-H23-F3-N2-O2
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MOLECULAR WEIGHT :
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344.42
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WISWESSER LINE NOTATION :
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FXFFR CO2U1 DVM2N2&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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1375 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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MPHEAE Medicina et Pharmacologia Experimentalis. (Basel, Switzerland) V.12-17, 1965-67. For publisher information, see PHMGBN. Volume(issue)/page/year: 15,241,1966
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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249 mg/kg
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TOXIC EFFECTS :
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Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation
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REFERENCE :
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JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 20,1,1970
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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86 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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MPHEAE Medicina et Pharmacologia Experimentalis. (Basel, Switzerland) V.12-17, 1965-67. For publisher information, see PHMGBN. Volume(issue)/page/year: 15,241,1966
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Mammal - dog
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DOSE/DURATION :
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40 mg/kg
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TOXIC EFFECTS :
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Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation
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REFERENCE :
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JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 20,1,1970
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