110283-79-9
110283-79-9 structure
- Name: CI-966
- Chemical Name: 1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid
- CAS Number: 110283-79-9
- Molecular Formula: C23H21F6NO3
- Molecular Weight: 473.40800
- Create Date: 2016-04-27 23:42:25
- Modify Date: 2025-08-24 09:00:15
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CI-966 (PD 126141) is a potent, selective inhibitor of the GABA transporter GAT-1 with IC50 of 0.26 and 1.2 uM for human and rat GAT-1, respectively.
| Name | 1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid |
|---|---|
| Synonyms |
1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydro-3-pyridine carboxylic acid
1-(2-(Bis(4-(trifluoromethyl)phenyl)methoxy)ethyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid CI-966 1,2,5,6-tetrahydro-1-<2-<bis<4-(trifluoromethyl)phenyl>methoxy>ethyl>-3-pyridinecarboxylic acid 3-Pyridinecarboxylicacid,1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydro Tocris-1296 |
| Density | 1.34g/cm3 |
|---|---|
| Boiling Point | 514.1ºC at 760mmHg |
| Molecular Formula | C23H21F6NO3 |
| Molecular Weight | 473.40800 |
| Flash Point | 264.7ºC |
| Exact Mass | 473.14300 |
| PSA | 49.77000 |
| LogP | 5.48480 |
| Vapour Pressure | 2.16E-11mmHg at 25°C |
| Index of Refraction | 1.517 |
| Precursor 4 | |
|---|---|
| DownStream 0 | |