Name | 2-amino-2-methylbutanedioic acid |
---|---|
Synonyms |
2-Amino-2-methylsuccinic acid
D-Aspartic acid,2-methyl-,hydrochloride (1:1) 2-Methylaspartic acid MFCD00056709 Aspartic acid,2-methyl 2-Amino-2-methyl-bernsteinsaeure |
Description | α-Methyl-DL-aspartic acid is a specific inhibitor of argininosuccinate synthase (ASS), and also is the rate-limiting enzyme for the recycling of 1-citrulline to 1-arginine[1]. |
---|---|
Related Catalog | |
In Vitro | α-methyl-dl-aspartic acid can significantly reduce the anti-hypertensive activity of Bj-BPP-10c in SHR[2]. |
In Vivo | α-methyl-dl-aspartic acid (147 mg/kg, i.v.) can diminish the l-citrulline-induced retinal vasodilation in Wistar rats[1]. Animal Model: Wistar rats Dosage: 147 mg/kg Administration: 147 mg/kg, i.v. Result: Attenuated the increase of retinal arteriolar diameter induced by L-citrulline. |
References |
Melting Point | 232-234ºC |
---|---|
Molecular Formula | C5H9NO4 |
Molecular Weight | 147.12900 |
Exact Mass | 147.05300 |
PSA | 100.62000 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
---|---|
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2922499990 |
HS Code | 2922499990 |
---|---|
Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |