117678-38-3

117678-38-3 structure

Name: Levofloxacin N-oxide
Chemical Name: Levofloxacin N-oxide
CAS Number: 117678-38-3
Molecular Formula: C₁₈H₂₀FN₃O₅
Molecular Weight: 377.367
Catalog: Research Areas Infection
Create Date: 2018-09-29 11:44:33
Modify Date: 2024-01-02 19:51:31
Levofloxacin N-oxide is a minor metabolite of Levofloxacin (HY-B0330). Levofloxacin N-oxide does not exhibit significantly genotoxic risks. Levofloxacin is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria[1][2].

Name	Levofloxacin N-oxide
Synonyms	unii-ue0e2o42uc (3S)-9-Fluoro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid 7H-1,4-Oxazino[2,3,4-ij]quinoline-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-, (3S)- Levofloxacin Impurity 1

Description	Levofloxacin N-oxide is a minor metabolite of Levofloxacin (HY-B0330). Levofloxacin N-oxide does not exhibit significantly genotoxic risks. Levofloxacin is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria[1][2].
Related Catalog	Research Areas >> Infection
References	[1]. Zhu Q, et al. In silico and in vitro genotoxicity evaluation of levofloxacin n-oxide, an impurity in levofloxacin. Toxicol Mech Methods. 2012 Apr;22(3):225-30. [2]. Nightingale CH, et al. Pharmacodynamics and pharmacokinetics of levofloxacin. Chemotherapy. 2000;46 Suppl 1:6-14.