10447-39-9
10447-39-9 structure
- Name: a-(3-quinuclidinyl)benzhydrol
- Chemical Name: 1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol
- CAS Number: 10447-39-9
- Molecular Formula: C20H24ClNO
- Molecular Weight: 293.403
- Catalog: Signaling Pathways GPCR/G Protein mAChR
- Create Date: 2018-05-27 08:00:00
- Modify Date: 2024-01-07 15:06:36
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Quifenadine (Compound 3a), the hydroxyl-(diphenyl)methyl quinuclidine derivative, is a M3 receptor antagonist with an IC50 value > 1000 nM. Quifenadine can be used for the research of neurological disease[1].
| Name | 1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol |
|---|---|
| Synonyms |
1-Azabicyclo[2.2.2]octane-3-methanol, α,α-diphenyl-
a,a-diphenyl-1-azabicyclo[2.2.2]octane-3-methanol Quifenadine (1-Aza-bicyclo[2.2.2]oct-3-yl)-diphenyl-methanol a-(3-quinuclidinyl)benzhydrol 1-Azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol Diphenyl-3-quinuclidylcarbinol Diphenyl-chinuclidin-3-yl-methanol Chinuclidyl-3-diphenyl-carbinol a,a-Diphenyl-3-quinuclidinemethanol |
| Description | Quifenadine (Compound 3a), the hydroxyl-(diphenyl)methyl quinuclidine derivative, is a M3 receptor antagonist with an IC50 value > 1000 nM. Quifenadine can be used for the research of neurological disease[1]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 430.2±30.0 °C at 760 mmHg |
| Melting Point | 239ºC |
| Molecular Formula | C20H24ClNO |
| Molecular Weight | 293.403 |
| Flash Point | 208.0±23.2 °C |
| Exact Mass | 293.177979 |
| PSA | 23.47000 |
| LogP | 3.63 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.641 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| HS Code | 2933990090 |
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~29%
10447-39-9 |
| Literature: Journal of Medicinal Chemistry, , vol. 52, # 8 p. 2493 - 2505 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |