62160-23-0

62160-23-0 structure

Name: 7-deazaguanosine
Chemical Name: 7-deazaguanosine
CAS Number: 62160-23-0
Molecular Formula: C₁₁H₁₄N₄O₅
Molecular Weight: 282.25
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-01-20 17:25:28
Modify Date: 2024-01-04 16:16:21
7-Deazaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	7-deazaguanosine
Synonyms	7-Desazaguanosin PELDESINE BCX-34

Description	7-Deazaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

115479-42-0

~92%

62160-23-0

Literature: Ramasamy; Imamura; Robins; Revankar Journal of Heterocyclic Chemistry, 1988 , vol. 25, # 6 p. 1893 - 1898

120401-36-7

~61%

62160-23-0

Literature: Seela; Soulimane; Mersmann; Jurgens Helvetica Chimica Acta, 1990 , vol. 73, # 7 p. 1879 - 1887

115479-40-8

62160-23-0

Literature: Journal of Heterocyclic Chemistry, , vol. 25, # 6 p. 1893 - 1898

84955-31-7

62160-23-0

Literature: Helvetica Chimica Acta, , vol. 73, # 7 p. 1879 - 1887

102690-95-9

62160-23-0

Literature: Helvetica Chimica Acta, , vol. 73, # 7 p. 1879 - 1887

76567-71-0

62160-23-0

Literature: Chemische Berichte, , vol. 114, # 10 p. 3395 - 3402

80153-20-4

62160-23-0

Literature: Chemische Berichte, , vol. 114, # 10 p. 3395 - 3402

80153-19-1

62160-23-0

Literature: Chemische Berichte, , vol. 114, # 10 p. 3395 - 3402