690632-55-4

690632-55-4 structure

Name: N-Succinimidyloxycarbonylpropyl methanethiosulfonate
Chemical Name: (2,5-dioxopyrrolidin-1-yl) 4-methylsulfonylsulfanylbutanoate
CAS Number: 690632-55-4
Molecular Formula: C₉H₁₃NO₆S₂
Molecular Weight: 295.33300
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2016-11-10 06:11:01
Modify Date: 2024-04-02 11:58:28
N-Succinimidyloxycarbonylpropyl methanethiosulfonate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	(2,5-dioxopyrrolidin-1-yl) 4-methylsulfonylsulfanylbutanoate
Synonyms	N-Succinimidyloxycarbonylpropyl Methanethiosulfonate MTS-4-NHS

Description	N-Succinimidyloxycarbonylpropyl methanethiosulfonate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.