68398-24-3

68398-24-3 structure

68398-24-3 structure

Name: methyl (5S)-8-methyl-4-thiophen-2-yl-8-azabicyclo[3.2.1]octane-3-carboxylate,hydrochloride
Chemical Name: methyl (5S)-8-methyl-4-thiophen-2-yl-8-azabicyclo[3.2.1]octane-3-carboxylate,hydrochloride
CAS Number: 68398-24-3
Molecular Formula: C₁₄H₂₀ClNO₂S
Molecular Weight: 301.83200
Create Date: 2017-08-14 17:34:56
Modify Date: 2024-02-08 16:20:48

Name	methyl (5S)-8-methyl-4-thiophen-2-yl-8-azabicyclo[3.2.1]octane-3-carboxylate,hydrochloride
Synonyms	methyl (5S)-8-methyl-4-thiophen-2-yl-8-azabicyclo[3.2.1]octane-3-carboxylate hydrochloride (+)-Methyl (1RS-exo,exo)-8-methyl-2-(2-thienyl)-8-azabicyclo(3.2.1)octane-3-carboxylate HCl 8-Azabicyclo(3.2.1)octane-3-carboxylic acid,8-methyl-2-(2-thienyl)-,methyl ester,hydrochloride,(1S-(exo,exo))

Molecular Formula	C₁₄H₂₀ClNO₂S
Molecular Weight	301.83200
Exact Mass	301.09000
PSA	57.78000
LogP	3.22730

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CL5603200

CHEMICAL NAME :: 8-Azabicyclo(3.2.1)octane-3-carboxylic acid, 8-methyl-2-(2-thienyl)-, methyl ester, hydrochloride, (1S-(exo,exo))-

CAS REGISTRY NUMBER :: 68398-24-3

LAST UPDATED :: 199101

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H19-N-O2-S.Cl-H

MOLECULAR WEIGHT :: 301.86

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 240 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy)

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 21,1243,1978