878143-33-0

878143-33-0 structure

Name: Dolasetron (Mesylate hydrate)
Chemical Name: UNII-U3C8E5BWKR component QTFFGPOXNNGTGZ-BEQIPBGHSA-M
CAS Number: 878143-33-0
Molecular Formula: C₂₀H₂₆N₂O₇S
Molecular Weight: 438.49
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2017-09-16 16:02:33
Modify Date: 2024-01-02 13:07:07
Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

Name	UNII-U3C8E5BWKR component QTFFGPOXNNGTGZ-BEQIPBGHSA-M
Synonyms	Dolasetron (Mesylate hydrate)

Description	Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor Research Areas >> Others
References	[1]. Faria C, et al. Outcomes Associated with 5-HT3-RA Therapy Selection in Patients with Chemotherapy-Induced Nausea and Vomiting: A Retrospective Claims Analysis. Am Health Drug Benefits. 2014 Jan;7(1):50-8. [2]. Schwartzberg L, et al. Pooled analysis of phase III clinical studies of palonosetron versus ondansetron, dolasetron, and granisetron in the prevention of chemotherapy-induced nausea and vomiting (CINV). Support Care Cancer. 2014 Feb;22(2):469-77.