149809-43-8

149809-43-8 structure

Name: (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
Chemical Name: [(3S,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methyl 4-methylbenzenesulfonate
CAS Number: 149809-43-8
Molecular Formula: C₂₁H₂₁F₂N₃O₄S
Molecular Weight: 449.471
Catalog: Pharmaceutical intermediate API intermediate
Create Date: 2018-07-12 18:57:53
Modify Date: 2024-01-02 14:12:03

Name	[(3S,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methyl 4-methylbenzenesulfonate
Synonyms	6-Methoxyaromadendrin 3-O-acetate 3-Furanmethanol, 5-(2,4-difluorophenyl)tetrahydro-2-methyl-5-(1H-1,2,4-triazol-1-yl)-, 4-methylbenzenesulfonate (ester), (2R,3S,5R)- 2,5-Anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-4-({[(4-methylphenyl)sulfonyl]oxy}methyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol [(2R,3S,5R)-5-(2,4-Difluorophenyl)-2-methyl-5-(1H-1,2,4-triazol-1-yl)tetrahydro-3-furanyl]methyl 4-methylbenzenesulfonate D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)- (5R-CIS)-TOLUENE-4-SULFONIC ACID 5-(2,4-DIFLUOROPHENYL)-5-(1 H-1,2,4-TRIAZOL-1-YL) METHYLTETRAHYDROFURAN-3-YLMETHYL ESTER Posaconazole Intermediate 2

Density	1.4±0.1 g/cm3
Boiling Point	600.3±65.0 °C at 760 mmHg
Melting Point	100-102°C
Molecular Formula	C₂₁H₂₁F₂N₃O₄S
Molecular Weight	449.471
Flash Point	316.8±34.3 °C
Exact Mass	449.122070
PSA	91.69000
LogP	2.59
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.616
Storage condition	-20°C Freezer, Under Inert Atmosphere