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38916-34-6

38916-34-6 structure
38916-34-6 structure
  • Name: Somatostatin-14
  • Chemical Name: somatostatin
  • CAS Number: 38916-34-6
  • Molecular Formula: C76H104N18O19S2
  • Molecular Weight: 1637.878
  • Catalog: API Hormone and endocrine-regulating drugs other
  • Create Date: 2018-08-23 19:05:30
  • Modify Date: 2024-01-02 14:23:25
  • Cyclic somatostatin is a growth hormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers. Sequence: H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: Cys3-Cys14).

Name somatostatin
Synonyms growth hormone inhibiting hormone
15-28-Somatostatin-28
Modustatina
SS-14
L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10-[(1S)-1-hydroxyethyl]-16-(1-hydroxyethyl)-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide
Somatostatin Acetate
Somatofalk
MFCD00076762
Stilamin
GH-RIF
SRIF-A
somatotropin release inhibiting factor
L-Alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine Cyclic (3®14) Disulfide
SRIF
Somatostatin
Somatostatina
EINECS 256-969-7
Aminopan
L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide
Glycinamide, L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-13,25,28-tris(phenylmethyl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacont-37-yl]-
Glycinamide, L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-4-carboxy-10-[(1S)-1-hydroxyethyl]-16-(1-hydroxyethyl)-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-13,25,28-tris(phenylmethyl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacont-37-yl]-
ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS: AGCKNFFWKTFTSC DISULFIDE BRIDGE CYS3-CYS14
Cyclic somatostatin
Description Cyclic somatostatin is a growth hormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers. Sequence: H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: Cys3-Cys14).
Related Catalog
Density 1.4±0.1 g/cm3
Boiling Point 1970.9±65.0 °C at 760 mmHg
Molecular Formula C76H104N18O19S2
Molecular Weight 1637.878
Flash Point 1145.7±34.3 °C
Exact Mass 1636.716675
PSA 663.83000
LogP -4.25
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.670
Storage condition −20°C
Water Solubility H2O: 1 mg/mL | Soluble in water(25,00°C 1,00 g/L), Methanol.
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS WF8751700

~95%

38916-34-6 structure

38916-34-6

Literature: Kitada, Shingo; Takahashi, Masahito; Yamaguchi, Yusuke; Okada, Yohei; Chiba, Kazuhiro Organic Letters, 2012 , vol. 14, # 23 p. 5960 - 5963

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38916-34-6 structure

38916-34-6

Literature: Shi, Tiesheng; Rabenstein, Dallas L. Journal of Organic Chemistry, 1999 , vol. 64, # 13 p. 4590 - 4595
Precursor  1

DownStream  0