133058-72-7

133058-72-7 structure

Name: KFM19
Chemical Name: 8-(3-oxocyclopentyl)-1,3-dipropyl-7H-purine-2,6-dione
CAS Number: 133058-72-7
Molecular Formula: C₁₆H₂₂N₄O₃
Molecular Weight: 318.37100
Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
Create Date: 2017-09-30 04:53:19
Modify Date: 2024-01-02 14:15:51
KFM19 is a potent, selective Adenosine receptor (A1-receptor) antagonist, with an IC50 of 50 nM.

Name	8-(3-oxocyclopentyl)-1,3-dipropyl-7H-purine-2,6-dione
Synonyms	(+,-)-8-(3-oxocyclopentyl)-1,3-dipropylxanthine 8-(3-oxocyclopentyl)-1,3-di-n-propyl-7H-purine-2,6-dione Biip 20 1,3-dipropyl-8-(3-oxocyclopentyl)-xanthine ((S)-(-)-8-(3-Oxocyclopentyl)-1,3-dipropyl-7H-purine-2,6-dione) Kfm 19 8-(3-Oxo-cyclopentyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione KFM19

Description	KFM19 is a potent, selective Adenosine receptor (A1-receptor) antagonist, with an IC50 of 50 nM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor Research Areas >> Neurological Disease
Target	IC50: 50 nM (Adenosine receptor)[1]
References	[1]. W.D. Bechtel, et al. KFM 19 antagonizes the adenosine-induced inhibition of electrically evoked acetylcholine release. Eur Neuropsychopharmacol. Sep. 1993, 3(3), Page 433