142717-57-5

142717-57-5 structure

Name: Dihydrocurcumenone
Chemical Name: (1R,6S,7R)-7-[(3S)-3-hydroxybutyl]-6-methyl-3-propan-2-ylidenebicyclo[4.1.0]heptan-4-one
CAS Number: 142717-57-5
Molecular Formula: C₁₅H₂₄O₂
Molecular Weight: 236.35000
Catalog: Research Areas Cardiovascular Disease
Create Date: 2016-04-05 14:45:25
Modify Date: 2024-01-21 19:05:10
Dihydrocurcumenone is a carabrane-type sesquiterpene. Dihydrocurcumenone can be isolated from Curcuma zedoaria, and the common form is 4-dihydrocurcumenone. Curcuma zedoaria sesquiterpene has vascular relaxation activity. 4-dihydrocurcumenone can inhibit the high concentration of K+ induced constriction of isolated rat aortic strips[1].

Name	(1R,6S,7R)-7-[(3S)-3-hydroxybutyl]-6-methyl-3-propan-2-ylidenebicyclo[4.1.0]heptan-4-one
Synonyms	dihydrocurcumenone

Description	Dihydrocurcumenone is a carabrane-type sesquiterpene. Dihydrocurcumenone can be isolated from Curcuma zedoaria, and the common form is 4-dihydrocurcumenone. Curcuma zedoaria sesquiterpene has vascular relaxation activity. 4-dihydrocurcumenone can inhibit the high concentration of K+ induced constriction of isolated rat aortic strips[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Yoshikawa M, et al. Absolute stereostructures of carabrane-type sesquiterpenes, curcumenone, 4S-dihydrocurcumenone, and curcarabranols A and B: Vasorelaxant activity of zedoary sesquiterpenes[J]. Chemical and pharmaceutical bulletin, 1998, 46(7): 1186-1188.