160107-15-3

160107-15-3 structure

Name: N4-Benzoyl-5-methylcytidine
Chemical Name: N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
CAS Number: 160107-15-3
Molecular Formula: C₁₇H₁₉N₃O₆
Molecular Weight: 361.35
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-05-01 02:51:10
Modify Date: 2024-01-09 19:26:27
N4-Benzoyl-5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
Synonyms	N-benzoyl-5-methylcytidine N4-Benzoyl-5-methyl cytidine Cytidine,N-benzoyl-5-methyl

Description	N4-Benzoyl-5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

93-97-0

2140-61-6

160107-15-3

Literature: Alnylam Pharmaceuticals, Inc. Patent: US2006/35254 A1, 2006 ;

554-01-8

160107-15-3

Literature: Wang, Shaohui; Xu, Yanzheng; Kool, Eric T. Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 6 p. 1043 - 1050

32865-88-6

160107-15-3

Literature: Wang, Shaohui; Xu, Yanzheng; Kool, Eric T. Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 6 p. 1043 - 1050

59237-68-2

160107-15-3

Literature: Wang, Shaohui; Xu, Yanzheng; Kool, Eric T. Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 6 p. 1043 - 1050

98-88-4

2140-61-6

160107-15-3

Literature: Wang, Shaohui; Xu, Yanzheng; Kool, Eric T. Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 6 p. 1043 - 1050