442633-00-3
442633-00-3 structure
- Name: CK 666
- Chemical Name: 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide
- CAS Number: 442633-00-3
- Molecular Formula: C18H17FN2O
- Molecular Weight: 296.33900
- Catalog: Signaling Pathways Cytoskeleton Arp2/3 Complex
- Create Date: 2016-12-14 08:49:27
- Modify Date: 2025-08-25 13:02:12
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CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex, and binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation[1].
| Name | 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide |
|---|---|
| Synonyms |
2-fluoro-N-(2-(2-methyl-1H-indol-3-yl)ethyl)benzamide
CK-666 |
| Description | CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex, and binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation[1]. |
|---|---|
| Related Catalog | |
| Target |
Arp2/3 complex[1] |
| References |
| Molecular Formula | C18H17FN2O |
|---|---|
| Molecular Weight | 296.33900 |
| Exact Mass | 296.13200 |
| PSA | 48.38000 |
| LogP | 4.16270 |
| RIDADR | NONH for all modes of transport |
|---|
