59892-36-3

59892-36-3 structure
59892-36-3 structure
  • Name: 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one
  • Chemical Name: 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one
  • CAS Number: 59892-36-3
  • Molecular Formula: C10H12N2O7
  • Molecular Weight: 272.21
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2017-12-17 20:44:40
  • Modify Date: 2024-01-03 11:43:49
  • 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one
Synonyms 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-nitropyridin-2-one
Description 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Molecular Formula C10H12N2O7
Molecular Weight 272.21
Exact Mass 272.06400
PSA 137.74000
Precursor  0

DownStream  1