CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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OH2900000
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CHEMICAL NAME :
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Leucine, N-(N-acetyl-3-(p-(bis(2-chloroethyl)amino)phenyl)-DL- alanyl)-, ethyl ester, L-
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CAS REGISTRY NUMBER :
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3577-89-7
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LAST UPDATED :
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199712
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C23-H35-Cl2-N3-O4
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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680 mg/kg/10D-I
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TOXIC EFFECTS :
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Related to Chronic Data - death
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REFERENCE :
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FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 33,472,1970
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intramuscular
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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215 mg/kg/10D-I
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TOXIC EFFECTS :
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Related to Chronic Data - death
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REFERENCE :
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FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 33,472,1970
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Rectal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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590 mg/kg/10D-I
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TOXIC EFFECTS :
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Related to Chronic Data - death
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REFERENCE :
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FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 33,472,1970
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