70-10-0

70-10-0 structure

Name: Ticlatone
Chemical Name: 6-chloro-1,2-benzothiazol-3-one
CAS Number: 70-10-0
Molecular Formula: C₇H₄ClNOS
Molecular Weight: 185.63100
Catalog: Biochemical Amino acids and their derivatives Cysteine derivative
Create Date: 2018-04-15 08:00:00
Modify Date: 2024-01-09 18:05:37
Ticlatone is an antifungal that can be used for the research of mycoses[1].

Name	6-chloro-1,2-benzothiazol-3-one
Synonyms	6-chlorobenzisothiazolinone 6-CHLORO-1,2-BENZISOTHIAZOL-3(2H)-ONE Ticlatonum [INN-Latin] 6-Chlor-3-oxo-2,3-dihydro-benzisothiazol TICLATONE 6-chloro-1,2-benzisothiazol-3-one 6-chlorobenzo[d]isothiazol-3-one Ticlatone [USAN:INN] Landromil Ticlatona [INN-Spanish] 6-chloro-1,2-benzisothiazolin-3-one Fer 1443 6-Chloro-1,2-benzisothiazolone

Description	Ticlatone is an antifungal that can be used for the research of mycoses[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Lundell E, et, al. [Clinical studies on landromil (tiklaton) in treatment of mycoses]. Mykosen. 1971 Nov 1;14(11):531-3.

Density	1.515 g/cm3
Melting Point	270-272ºC
Molecular Formula	C₇H₄ClNOS
Molecular Weight	185.63100
Exact Mass	184.97000
PSA	61.10000
LogP	2.24300
Index of Refraction	1.669
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DE4170000

CHEMICAL NAME :: 1,2-Benzisothiazolin-3-one, 6-chloro-

CAS REGISTRY NUMBER :: 70-10-0

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H4-Cl-N-O-S

MOLECULAR WEIGHT :: 185.63

WISWESSER LINE NOTATION :: T56 BSMVJ FG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >4300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,1306,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,1306,1964

HS Code	2934999090

176107-21-4

~95%

70-10-0

Literature: Sumitomo Seika Chemicals Co., Ltd.; HIYAMA, Takehiro; YOKOE, Ichiro; TAKEUCHI, Takeshi; SUZUKI, Michio Patent: EP2687519 A1, 2014 ; Location in patent: Paragraph 0047; 0048 ;

19993-68-1

70-10-0

Literature: Journal of Organic Chemistry, , vol. 53, # 12 p. 2850 - 2852

19993-69-2

70-10-0

Literature: Journal of Organic Chemistry, , vol. 53, # 12 p. 2850 - 2852

52948-12-6

70-10-0

Literature: Heterocycles, , vol. 51, # 12 p. 3005 - 3012

Precursor 1
52948-12-6
DownStream 1
131540-87-9

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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