Name | Ifetroban |
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Description | Ifetroban is a long-acting thromboxane A2 receptor antagonist, with antiplatelet activity[1]. |
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Related Catalog | |
Target |
Thromboxane A2 receptor[1] |
In Vitro | Ifetroban is a long-acting thromboxane/prostaglandin endoperoxide receptor antagonist, with antiplatelet activity[1]. |
In Vivo | Ifetroban (20, 40 mg/kg/day, i.p.) shows no effect on the blood pressure in stroke-prone spontaneously hypertensive rats[1]. Ifetroban (BMS 180,291; 1 and 3 mg/kg, p.o.) inhibits aggregation and antagonizes TP-receptor in monekys. Ifetroban (3 mg/kg, i.v.) causes only marginal and transient hemodynamic effects in anesthetized African green monkeys[2]. |
References |
Density | 1.206g/cm3 |
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Boiling Point | 663.6ºC at 760mmHg |
Molecular Formula | C25H32N2O5 |
Molecular Weight | 440.53200 |
Flash Point | 355.1ºC |
Exact Mass | 440.23100 |
PSA | 101.66000 |
LogP | 4.50640 |
Index of Refraction | 1.566 |