Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,2,4-Triazolidine-3,5-dione,1,2,4-tris(2-oxiranylmethyl)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

77658-97-0

77658-97-0 structure

77658-97-0 structure

Name: 1,2,4-Triazolidine-3,5-dione,1,2,4-tris(2-oxiranylmethyl)-
Chemical Name: 1,2,4-tris(oxiran-2-ylmethyl)-1,2,4-triazolidine-3,5-dione
CAS Number: 77658-97-0
Molecular Formula: C₁₁H₁₅N₃O₅
Molecular Weight: 269.25400
Create Date: 2018-10-02 21:39:47
Modify Date: 2024-01-05 18:47:10

Name	1,2,4-tris(oxiran-2-ylmethyl)-1,2,4-triazolidine-3,5-dione
Synonyms	EINECS 278-745-8 Anaxirone Anaxirona [Spanish] Anaxironum [Latin] Triglycidylurazole 1,2,4-Triglycidyl urazol

Density	1.596g/cm3
Boiling Point	405.8ºC at 760 mmHg
Molecular Formula	C₁₁H₁₅N₃O₅
Molecular Weight	269.25400
Flash Point	199.2ºC
Exact Mass	269.10100
PSA	86.52000
Index of Refraction	1.639

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XZ5437000

CHEMICAL NAME :: 1,2,4-Triazolidine-3,5-dione, 1,2,4-tris(oxiranylmethyl)-

CAS REGISTRY NUMBER :: 77658-97-0

LAST UPDATED :: 199703

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C11-H15-N3-O5

MOLECULAR WEIGHT :: 269.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 9,209,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJCODS European Journal of Cancer and Clinical Oncology. (Pergamon Press, c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.17(7)- 25, 1981-89. For publisher information, see EJCAEL Volume(issue)/page/year: 20,1187,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 27,67,1993

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 70 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 9,209,1984

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Blood - hemorrhage

REFERENCE :: CCPHDZ Cancer Chemotherapy and Pharmacology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1978- Volume(issue)/page/year: 27,361,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 75 mg/kg/3D-I

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Blood - thrombocytopenia Related to Chronic Data - death

REFERENCE :: CCPHDZ Cancer Chemotherapy and Pharmacology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1978- Volume(issue)/page/year: 27,361,1991