Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: mebanazine
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Purity: 98.0%
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65-64-5

65-64-5 structure

65-64-5 structure

Name: mebanazine
Chemical Name: 1-phenylethylhydrazine
CAS Number: 65-64-5
Molecular Formula: C₈H₁₂N₂
Molecular Weight: 136.194
Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
Create Date: 2018-02-22 08:00:00
Modify Date: 2024-01-12 13:43:09
Mebanazine is a potent monoamine oxidase (MAO) inhibitor. Mebanazine can be used in research of depression[1].

Name	1-phenylethylhydrazine
Synonyms	EINECS 200-615-6 Mebanazina [INN-Spanish] a-Methylbenzylhydrazine actamol mebanazine Phenylethylhydrazine Mebenazine 1-(1-phenylethyl)hydrazine Hydrazine, (1-phenylethyl)- (+/-)-(1-Phenylethyl)hydrazin Actomol Mebanazinum [INN-Latin] (1-Phenylethyl)hydrazine a-Phenethyl Hydrazine

Description	Mebanazine is a potent monoamine oxidase (MAO) inhibitor. Mebanazine can be used in research of depression[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
In Vivo	Mebanazine (90 mg/kg; i.p.; once; mature female rats) decreases the blood giucose level[1]. Mebanazine (1-60 mg/kg; i.p.; once; mature female rats) has the minimal dose which lowered blood glucose after 12 h is 60 mg/kg[1]. Animal Model: Mature female rats[1] Dosage: 90 mg/kg Administration: Intraperitoneal injection; once Result: Decreased the blood giucose level after 4-8 h, and continues for 2 days. Animal Model: Mature female rats[1] Dosage: 0-60 mg/kg Administration: Intraperitoneal injection; once Result: Decreased the blood giucose level in a dose-dependent manner.
References	[1]. Mishkinsky UZ, et. al. The hypoglycaemic effect of mebanazine (Actomol) and its mechanism. Biochemical Pharmacology. 1965;14(7):1059-64.

Density	1.0±0.1 g/cm3
Boiling Point	262.1±19.0 °C at 760 mmHg
Molecular Formula	C₈H₁₂N₂
Molecular Weight	136.194
Flash Point	129.6±25.1 °C
Exact Mass	136.100052
PSA	38.05000
LogP	1.07
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.546

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MV5650000

CHEMICAL NAME :: Hydrazine, (alpha-methylbenzyl)-

CAS REGISTRY NUMBER :: 65-64-5

LAST UPDATED :: 198812

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H12-N2

MOLECULAR WEIGHT :: 136.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 225 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 238,62,1960

RIDADR	UN 1851
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2928000090

HS Code	2928000090
Summary	2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%