- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Ac-IETD-pNA
- Price: Check
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- GL Biochem (Shanghai) Ltd.
- China
- Product Name: Caspase 8 Substrate 1m, fluorogenic;Ac-IETD-AMC
- Price: $Inquiry/1kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Jackie Yang
- Email: ymbetter@glbiochem.com
- DC Chemicals Limited
- China
- Product Name: Caspase-8 Chromogenic Substrate I
- Price: $950.0/100mg $1900.0/250mg $3800.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Caspase-8 Chromogenic Substrate I
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- Nanjing Peptide Biotech Ltd
- China
- Product Name: Ac-Ile-Glu-Thr-Asp-pNA
- Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
- Purity: 98.0%
- Stocking Period: 7 Day
- Contact: jom
- Email: chenglong.fan@njpeptide.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: AC-IETD-PNA
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
219138-21-3
219138-21-3 structure
- Name: Ac-Ile-Glu-Thr-Asp-pNA
- Chemical Name: ac-ietd-pna
- CAS Number: 219138-21-3
- Molecular Formula: C27H38N6O12
- Molecular Weight: 638.624
- Catalog: Research Areas Others
- Create Date: 2018-11-24 12:19:14
- Modify Date: 2025-08-22 11:11:44
-
Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity[1].
| Name | ac-ietd-pna |
|---|---|
| Synonyms |
ac-ietd-amc
z-ala-ala-asp-afc N-Acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-nitrophenyl)-L-α-asparagine ac-ile-glu-thr-asp-mca ac-ietd-mca L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-nitrophenyl)- pase-8 substrate pase-8 substrate i ac-ile-glu-thr-asp-amc ax-ietd-amc granzyme b substrate |
| Description | Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 1140.8±65.0 °C at 760 mmHg |
| Molecular Formula | C27H38N6O12 |
| Molecular Weight | 638.624 |
| Flash Point | 643.7±34.3 °C |
| Exact Mass | 638.254761 |
| PSA | 286.15000 |
| LogP | 1.27 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.583 |