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82909-47-5

82909-47-5 structure
82909-47-5 structure
  • Name: Alkynyl myristic acid
  • Chemical Name: tetradec-13-ynoic acid
  • CAS Number: 82909-47-5
  • Molecular Formula: C14H24O2
  • Molecular Weight: 224.339
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-12-04 05:35:42
  • Modify Date: 2024-01-11 22:24:42
  • Alkynyl myristic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name tetradec-13-ynoic acid
Synonyms 13-Tetradecynoic acid
Myristic Acid Alkyne
Tetradec-13-ynoic acid
Tetradec-13-insaeure
13-Tetradecyn-1-oic acid
Description Alkynyl myristic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 0.9±0.1 g/cm3
Boiling Point 341.6±15.0 °C at 760 mmHg
Molecular Formula C14H24O2
Molecular Weight 224.339
Flash Point 165.8±15.1 °C
Exact Mass 224.177628
PSA 37.30000
LogP 4.74
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.469