123018-47-3
123018-47-3 structure
- Name: Atiprimod
- Chemical Name: 3-(8,8-dipropyl-2-azaspiro[4.5]decan-2-yl)-N,N-diethylpropan-1-amine
- CAS Number: 123018-47-3
- Molecular Formula: C22H44N2
- Molecular Weight: 336.59800
- Create Date: 2016-06-09 05:34:05
- Modify Date: 2026-07-15 00:32:57
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Atiprimod (SKF 106615, Azaspirane) is a potent, orally bioavailable JAK2 inhibitor, inhibits phosphorylation of JAK2 and the downstream STAT3 and STAT5 pathways.
| Name | 3-(8,8-dipropyl-2-azaspiro[4.5]decan-2-yl)-N,N-diethylpropan-1-amine |
|---|---|
| Synonyms |
2-Azaspiro(4.5)decane-2-propanamine,N,N-diethyl-8,8-dipropyl
3-(8,8-dipropyl-2-azaspirodecan-2-yl)-N,N-diethylpropan-1-amine Azaspirane 2-Azaspirodecane-2-propanamine, N,N-diethyl-8,8-dipropyl Atiprimod [INN] UNII-MG7D3QD743 Atiprimod (free base) N,N-diethyl-8,8-dipropyl-2-azaspiro[4,5]decane-2-propanamamine Atiprimod (SKF SK&F N,N-diethyl-8,8-dipropyl-2-azaspiro[4,5]decane-2-propanamine |
| Density | 0.91g/cm3 |
|---|---|
| Boiling Point | 390ºC at 760mmHg |
| Molecular Formula | C22H44N2 |
| Molecular Weight | 336.59800 |
| Flash Point | 166.5ºC |
| Exact Mass | 336.35000 |
| PSA | 6.48000 |
| LogP | 5.50890 |
| Precursor 10 | |
|---|---|
| DownStream 0 | |
![3-(14,14-dipropyl-1,4-dithia-9-azadispiro[4.1.47.35]tetradecan-9-yl)-N,N-diethylpropan-1-amine structure](https://image.chemsrc.com/caspic/251/253335-95-4.png)
![2-(3-(diethylamino)propyl)-7,9-dimethoxy-2-azaspiro[4.5]deca-6,9-dien-1-one structure](https://image.chemsrc.com/caspic/129/253333-59-4.png)
![2-(3-(diethylamino)propyl)-7,9-dimethoxy-8-propyl-2-azaspiro[4.5]deca-6,9-dien-1-one structure](https://image.chemsrc.com/caspic/454/255918-60-6.png)
![3-(7,9-dimethoxy-8,8-dipropyl-2-azaspiro[4.5]deca-6,9-dien-2-yl)-N,N-diethylpropan-1-amine structure](https://image.chemsrc.com/caspic/236/253333-61-8.png)
![2-(3-(diethylamino)propyl)-8,8-dipropyl-2-azaspiro[4.5]decan-7-one structure](https://image.chemsrc.com/caspic/289/253335-94-3.png)
![2-(3-(diethylamino)propyl)-8,8-dipropyl-2-azaspiro[4.5]decane-7,9-dione structure](https://image.chemsrc.com/caspic/198/253333-62-9.png)
