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70146-78-0

70146-78-0 structure
70146-78-0 structure
  • Name: Diethyl-(4-brombenzyl)malonat
  • Chemical Name: diethyl 2-[(4-bromophenyl)methyl]propanedioate
  • CAS Number: 70146-78-0
  • Molecular Formula: C14H17BrO4
  • Molecular Weight: 329.186
  • Create Date: 2018-12-25 11:14:58
  • Modify Date: 2024-01-03 17:38:02

Name diethyl 2-[(4-bromophenyl)methyl]propanedioate
Synonyms Diethyl (4-bromobenzyl)malonate
Diethyl-(4-brombenzyl)malonat
Propanedioic acid, 2-[(4-bromophenyl)methyl]-, diethyl ester
Density 1.3±0.1 g/cm3
Boiling Point 375.7±27.0 °C at 760 mmHg
Molecular Formula C14H17BrO4
Molecular Weight 329.186
Flash Point 181.0±23.7 °C
Exact Mass 328.031006
PSA 52.60000
LogP 3.53
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.523

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70146-78-0 structure

70146-78-0

Literature: VITAE PHARMACEUTICALS, INC.; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; CACATIAN, Salvacion; CLAREMON, David, A.; DILLARD, Lawrence, W.; FUCHS, Klaus; HEINE, Niklas; JIA, Lanqi; LEFTHERIS, Katerina; MCKEEVER, Brian; MORALES-RAMOS, Angel; SINGH, Suresh; VENKATRAMAN, Shankar; WU, Guosheng; WU, Zhongren; XU, Zhenrong; YUAN, Jing; ZHENG, Yajun Patent: WO2010/105179 A2, 2010 ; Location in patent: Page/Page column 76 ; WO 2010/105179 A2

~49%

70146-78-0 structure

70146-78-0

Literature: Ward, Richard A.; Brassington, Claire; Breeze, Alexander L.; Caputo, Alessandro; Critchlow, Susan; Davies, Gareth; Goodwin, Louise; Hassall, Giles; Greenwood, Ryan; Holdgate, Geoffrey A.; Mrosek, Michael; Norman, Richard A.; Pearson, Stuart; Tart, Jonathan; Tucker, Julie A.; Vogtherr, Martin; Whittaker, David; Wingfield, Jonathan; Winter, Jon; Hudson, Kevin Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3285 - 3306

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70146-78-0 structure

70146-78-0

Literature: Huang, Wen; Zheng, Pengzhi; Zhang, Zhengxing; Liu, Rutting; Chen, Zhenxia; Zhou, Xigeng Journal of Organic Chemistry, 2008 , vol. 73, # 17 p. 6845 - 6848

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70146-78-0 structure

70146-78-0

Literature: Kuwabara, Kenji; Aoki, Tomiyoshi Patent: US2003/166697 A1, 2003 ;