42863-81-0

42863-81-0 structure
42863-81-0 structure
  • Name: 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-one
  • Chemical Name: 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-one
  • CAS Number: 42863-81-0
  • Molecular Formula: C14H9Cl2N3O2
  • Molecular Weight: 322.14600
  • Create Date: 2018-07-07 12:58:32
  • Modify Date: 2024-04-05 19:27:05
  • Lopirazepam is a potent small molecule GABAA receptor agonist, which can be used to treat anxiety disorders, insomnia, epilepsy and other diseases.

Name 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-one
Synonyms Lopirazepam [INN]
2H-Pyrido(3,2-e)-1,4-diazepin-2-one,1,3-dihydro-7-chloro-5-(2-chlorophenyl)-3-hydroxy
3-Hydroxy-5-o-chlorophenyl-6-aza-7-chloro-1,2-dihydro-3H-1,4-benzodiazepinone
EINECS 255-974-1
Lopirazepamum [INN-Latin]
2H-Pyrido(3,2-e)-1,4-diazepin-2-one,7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy
7-chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-pyrido[3,2-e][1,4]diazepin-2-one
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2h-pyrido[3,2-e][1,4]diazepin-2-one
7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-pyrido(3,2-e)-1,4-diazepin-2-one
Lopirazepam
Description Lopirazepam is a potent small molecule GABAA receptor agonist, which can be used to treat anxiety disorders, insomnia, epilepsy and other diseases.
References 1. Fabian A,et al. Veränderungen der Dauer der Schlafzyklen unter Flurazepam und Lopirazepam [Changes in the length of sleep cycles during administration of flurazepam and lopirazepam]. EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1984 Sep;15(3):151-8. German.
Density 1.61g/cm3
Boiling Point 563.9ºC at 760mmHg
Molecular Formula C14H9Cl2N3O2
Molecular Weight 322.14600
Flash Point 294.8ºC
Exact Mass 321.00700
PSA 78.07000
LogP 2.01700
Index of Refraction 1.726