138490-53-6

138490-53-6 structure

Name: WAY-123398
Chemical Name: 4-(methanesulfonamido)-N-methyl-N-[2-[methyl-(1-methylbenzimidazol-2-yl)amino]ethyl]benzenesulfonamide
CAS Number: 138490-53-6
Molecular Formula: C₁₉H₂₅N₅O₄S₂
Molecular Weight: 451.56300
Catalog: Research Areas Cardiovascular Disease
Create Date: 2017-07-25 22:53:17
Modify Date: 2024-02-19 14:32:15
WAY-123398 is a class III antiarrhythmic agent. WAY-123398 is a selective blocker of the delayed rectifier K+ current[1].

Name	4-(methanesulfonamido)-N-methyl-N-[2-[methyl-(1-methylbenzimidazol-2-yl)amino]ethyl]benzenesulfonamide
Synonyms	N-methyl-N-<2-<methyl(1-methyl-1H-benzimidazol-2-yl)amino>ethyl>-4-<(methylsulfonyl)amino>benzenesulfonamide N-Methyl-N-(2-(methyl(1-methyl-1H-benzimidazol-2-yl)amino)ethyl)-4-((methylsulfonyl)amino)benzenesulfonamide hcl Way-123,398 Benzenesulfonamide,N-methyl-N-(2-(methyl(1-methyl-1H-benzimidazol-2-yl)amino)ethyl)-4-((methylsulfonyl)amino)

Description	WAY-123398 is a class III antiarrhythmic agent. WAY-123398 is a selective blocker of the delayed rectifier K+ current[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Spinelli W, et al. Cellular electrophysiology of WAY-123,398, a new class III antiarrhythmic agent: specificity of IK block and lack of reverse use dependence in cat ventricular myocytes. Cardiovasc Res. 1993 Sep;27(9):1580-91. [2]. Spinelli W,et al. Effects of WAY-123,398, a new class III antiarrhythmic agent, on cardiac refractoriness and ventricular fibrillation threshold in anesthetized dogs: a comparison with UK-68798, E-4031, and dl-sotalol. J Cardiovasc Pharmacol. 1992 Dec;20(6):913-22.