890091-43-7

890091-43-7 structure

Name: Boc-amido-PEG9-amine
Chemical Name: tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
CAS Number: 890091-43-7
Molecular Formula: C₂₅H₅₂N₂O₁₁
Molecular Weight: 556.68700
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-10-08 21:38:34
Modify Date: 2024-04-03 15:39:25
Boc-amido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
Synonyms	O-(2-Aminoethyl)-O inverted exclamation marka-[2-(Boc-amino)ethyl]octaethylene glycol O-(2-aminoethyl)-O'-[2-(Boc-amino)ethyl]octaethylene glycol Boc-PEG-amine (n=9) (2-{2-[2-(2-{2-[2-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}-ethoxy)ethoxy]ethoxy}ethyl)carbamic acid tert-butyl ester

Description	Boc-amido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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